splicing.py

import string
import sys
from collections import OrderedDict

comp={'A':'T','T':'A','G':'C','C':'G'}
value,key="",""
s=OrderedDict({})


with open("rosalind_splc.txt","rU") as f:
    for x in f:
        if x[0]!=">":
            value=value+x.strip()
        else:
            if key!="": 
                s[key]=value
                value=""
            key=x[1:].strip()
    s[key]=value
f.close()


rna={}
f=open('rna_table.txt','rU')
for line in f:
    x=line.split()
    codons=x[0::2]
    acids=x[1::2]
    rna_new=dict(zip(codons,acids))
    rna.update(rna_new)

f.close()


dna=s.values()[0]

for value in s.values()[1:]:

    while value in dna:
        j=dna.find(value)
        t=len(value)
        dna=dna[0:j]+dna[j+t:]

dna=dna.replace("T","U")
    
for i in range(0,len(dna),3):
    if rna[dna[i:i+3]]=='Stop':
        sys.stdout.write('\n')
        break
    sys.stdout.write(rna[dna[i:i+3]]),